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· Priemel M, von Domarus C, Klatte To help you mais aussi al ·

Priemel M, von Domarus C, Klatte To help you mais aussi al

Priemel M, von Domarus C, Klatte To help you mais aussi al

Limbs mineralization defects and you will nutritional D deficit: histomorphometric research away from iliac crest bones biopsies and you can dispersing 25-hydroxyvitamin D inside 675 customers. J Limbs Miner Res 2010; 25: 305–312.

Zhou Y, Zhao LJ, Xu X et al. DNA methylation degrees of CYP2R1 and you can CYP24A1 predict supplement D reaction type. J Steroid Biochem Mol Biol 2014; 144: 207–214.

Ralston SH, Binkley N, Boonen S ainsi que al. Randomized trial out of alendronate and additionally supplement D3 in place of fundamental proper care within the osteoporotic postmenopausal lady with vitamin D deficit. Calcif Structure Int 2011; 88: 485–494.

Weber K, Kaschig C, Erben RG . step 1 Leader-hydroxyvitamin D2 and 1 alpha-hydroxyvitamin D3 features anabolic consequences toward cortical limbs, however, induce intracortical restorations at poisonous dosages inside ovariectomized mice. Bones 2004; 35: 704–710.

Li M, Healy DR, Simmons HA mais aussi al. Alfacalcidol regulates cancellous bone when you look at the ovariectomized rats. J Musculoskelet Neuronal Come together 2003; 3: 39–46.

Cures having elage, and you may collagen crosslinks in primate limbs

Orimo H, Shiraki Yards, Hayashi Y ainsi que al. Aftereffects of step one leader-hydroxyvitamin D3 to your lumbar limbs mineral occurrence and you may spinal cracks from inside the clients that have postmenopausal osteoporosis. Calcif Structure Int 1994; 54: 370–376.

Shikari Kushida Yards, Yamazaki K, Nagai K ainsi que al. H. Ramifications of dos years’ treatments for weakening of bones with step 1 alpha-hydroxy nutritional D3 to the bone mineral thickness and you may incidence out of fracture: a good placebo-regulated, double-blind potential data. Endocr J 1996; 43: 211–220.

Nuti R, Bianchi Grams, Brandi ML ainsi que al. Excellence regarding alfacalcidol than the supplement D including calcium from inside the lumbar bone nutrient density in postmenopausal weakening of bones. Rheumatol Int 2006; 26: 445–453.

Kubodera N, Tsuji Letter, Uchiyama Y et al. Another type of energetic vitamin D analog, ED-71, grounds increase in bone mass with preferential consequences toward bones in the osteoporotic customers. J Mobile Biochem 2003; 88: 286–289.

Abe Yards, Tsuji N, Takahashi F et al. Post on brand new logical pharmacokinetics of elin D3 by-product. Jpn Pharmacol Ther 2011; 39: 261–274.

Ritter CS, Brown AJ . Inhibition from PTH by the supplement D analog eldecalcitol was modulated by the their highest attraction towards the solution nutritional D-binding protein and effectiveness metabolic rate. J Telephone Biochem 2011; 112: 1348–1352.

Kondo S, Takano T, Ono Y et al. Eldecalcitol decrease osteoporotic fractures of the book systems. J Steroid Biochem Mol Biol 2015; 148: 232–238.

Harada S, Mizoguchi T, Kobayashi Y et al. Daily government regarding elin D analogue, develops limbs nutrient thickness from the inhibiting RANKL term inside the mouse trabecular limbs. J Limbs Miner Res 2012; 27: 461–473.

Hayashi Y, Fujita T, Inoue T

Matsumoto T, Ito Meters, Hayashi Y et al. A new active nutritional D3 analogue, eldecalcitol, suppresses the risk of osteoporotic cracks–a beneficial randomized, energetic comparator, double-blind study. Bones 2011; 49: 605–612.

Matsumoto T, Takano T, Saito H mais aussi al. Nutritional D analogs and bones: preclinical and you may clinical studies that have el; 3: 513.

Sakai An excellent, Ito Yards, Tomomitsu T mais aussi al. Effectiveness out of shared medication with alendronate (ALN) and you may elin D analogue, to that particular of concomitant ALN, supplement D and calcium supplements procedures in Japanese people with pri; 26: 1193–1202.

Plum La, Fitzpatrick Los angeles, Ma X ainsi que al. 2MD, an alternate anabolic agent getting weakening of bones treatment. Osteoporos Int 2006; 17: 704–715.

Ke HZ, Qi H, Crawford DT mais aussi al. An alternate vitamin D analog, 2MD, restores trabecular and cortical bones size and you can fuel in ovariectomized rats which have established osteopenia. J Limbs Miner Res 2005; 20: 1742–1755.

DeLuca HF, Bedale W, Binkley N et al. Brand new nutritional D analog 2MD develops limbs turnover however BMD inside the postmenopausal girls having osteopenia: outcome of a-1-year phase 2 twice-blind, placebo-controlled, randomized clinical test. J Limbs Miner Res 2011; 26: 538–545.

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